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1

Coumarin and Isocoumarin as Serine Protease Inhibitors

Pochet, Lionel, Frederick, Raphael, Masereel, Bernard

Journal:

Current Pharmaceutical Design

Year:

2004

Language:

english

File:

PDF, 314 KB

english, 2004

2

Synthesis of Nimesulide Nanoparticles in the Microemulsion Epikuron/Isopropyl Myristate/Water/n-Butanol (or Isopropanol)

F. Debuigne, J. Cuisenaire, L. Jeunieau, B. Masereel, J.B. Nagy

Journal:

Journal of Colloid and Interface Science

Year:

2001

Language:

english

File:

PDF, 413 KB

english, 2001

3

Carbonic anhydrase inhibitors: aromatic and heterocyclic sulfonamides incorporating adamantyl moieties with strong anticonvulsant activity

Marc A Ilies, Bernard Masereel, Stéphanie Rolin, Andrea Scozzafava, Gheorghe Câmpeanu, Valentin Cı̂mpeanu, Claudiu T Supuran

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 347 KB

english, 2004

4

Antibody immobilization on gold nanoparticles coated layer-by-layer with polyelectrolytes

Bernard Masereel, Mustapha Dinguizli, Caroline Bouzin, Nicolas Moniotte, Olivier Feron, Bernard Gallez, Thierry Vander Borght, Carine Michiels, Stéphane Lucas

Journal:

Journal of Nanoparticle Research

Year:

2011

Language:

english

File:

PDF, 449 KB

english, 2011

5

Design, synthesis and biological evaluation of a sulfonylcyanoguanidine as thromboxane A2 receptor antagonist and thromboxane synthase inhibitor

Jean-Michel Dogné, Johan Wouters, Stéphanie Rolin, Catherine Michaux, Lionel Pochet, François Durant, Jacques Delarge, Bernard Masereel

Journal:

Journal of Pharmacy and Pharmacology

Year:

2001

Language:

english

File:

PDF, 293 KB

english, 2001

6

Radioimmunotherapy with radioactive nanoparticles: Biological doses and treatment efficiency for vascularized tumors with or without a central hypoxic area

Bouchat, V., Nuttens, V. E., Michiels, C., Masereel, B., Feron, O., Gallez, B., Vander Borght, T., Lucas, S.

Journal:

Medical Physics

Year:

2010

Language:

english

File:

PDF, 400 KB

english, 2010

7

ChemInform Abstract: First Synthesis of 4-Substituted Benzenesulfonylcyanoguanidines.

B. MASEREEL, P. LEBRUN, J. M. DOGNE, P. DE TULLIO, B. PIROTTE, L. POCHET, O. DIOUF, J. DELARGE

Journal:

Year:

1997

File:

PDF, 29 KB

1997

8

ChemInform Abstract: Synthesis and Biological Evaluation of Sulfonylcyanoguanidines and Sulfonamidonitroethylenes as Bioisosteres of Hypoglycemic Sulfonylureas.

B. MASEREEL, R. OUEDRAOGO, J. M. DOGNE, M. H. ANTOINE, P. DE TULLIO, B. PIROTTE, L. POCHET, J. DELARGE, P. LEBRUN

Journal:

Year:

1997

File:

PDF, 28 KB

1997

9

ChemInform Abstract: “Fries Like” Rearrangement: A Novel and Efficient Method for the Synthesis of 6-Acyl-2(3H)-benzoxazolones and 6-Acyl-2(3H)-benzothiazolones.

H. UCAR, K. VAN DERPOORTEN, P. DEPOVERE, D. LESIEUR, M. ISA, B. MASEREEL, J. DELARGE, J. H. POUPAERT

Journal:

Year:

1998

File:

PDF, 34 KB

1998

10

ChemInform Abstract: Synthesis and Anticonvulsant Activity of 2(3H)-Benzoxazolone and 2(3H)-Benzothiazolone Derivatives.

H. UCAR, K. VAN DERPOORTEN, S. CACCIAGUERRA, S. SPAMPINATO, J. P. STABLES, P. DEPOVERE, M. ISA, B. MASEREEL, J. DELARGE, J. H. POUPAERT

Journal:

Year:

1998

File:

PDF, 28 KB

1998

11

ChemInform Abstract: Design, Synthesis, and Anticonvulsant Activity of 1-(Pyrid-3-ylsulfonamido)-2-nitroethylenes.

B. MASEREEL, J. WOUTERS, L. POCHET, D. LAMBERT

Journal:

Year:

1998

File:

PDF, 32 KB

1998

12

ChemInform Abstract: Synthesis, Structural Characterization and Thromboxane A2 Receptor Antagonistic Activity of 3-Substituted 2-[(Arylsulfonyl)imino]-2,3-dihydrothiazolyl Derivatives.

Fabrice Lacan, Martine Varache-Lembege, Joseph Vercauteren, Jean-Michel Leger, Bernard Masereel, Jean-Michel Dogne, Alain Nuhrich

Journal:

Year:

1999

File:

PDF, 31 KB

1999

13

ChemInform Abstract: Terbogrel, a Dual-Acting Agent for Thromboxane Receptor Antagonism and Thromboxane Synthase Inhibition.

Catherine Michaux, Bernadette Norberg, Jean-Michel Dogne, Francois Durant, Bernard Masereel, Jacques Delarge, Johan Wouters

Journal:

Year:

2001

File:

PDF, 29 KB

2001

14

ChemInform Abstract: Novel Inhibitors of the Sodium—Calcium Exchanger: Benzene Ring Analogues of N-Guanidino Substituted Amiloride Derivatives.

Bernard Masereel, et al. et al.

Journal:

Year:

2002

File:

PDF, 33 KB

2002

15

N-tert-Butyl-N′-(2-cyclohexylamino-5-nitrobenzenesulfonyl)urea, BM531, a Dual-Acting Agent for Thromboxane Receptor Antagonism and Thromboxane Synthase Inhibition.

Catherine Michaux, Jean-Michel Dogne, Bernadette Norberg, Francois Durant, Bernard Masereel

Journal:

Year:

2003

File:

PDF, 64 KB

2003

16

Exploration of the Binding Mode of Indanesulfonamides as Selective Inhibitors of Human Carbonic Anhydrase Type VII by Targeting Lys 91

Anne Thiry, Bernard Masereel, Jean-Michel Dogné, Claudiu T. Supuran, Johan Wouters, Catherine Michaux

Journal:

Year:

2007

Language:

english

File:

PDF, 867 KB

english, 2007

17

Carbonic Anhydrase Inhibitors: Binding of Indanesulfonamides to the Human Isoform II

Katia D'Ambrosio, Bernard Masereel, Anne Thiry, Andrea Scozzafava, Claudiu T. Supuran, Giuseppina De Simone

Journal:

Year:

2008

Language:

english

File:

PDF, 378 KB

english, 2008

18

Structural Study of Pinacidil, a Potassium-Channel Opener Belonging to the chemical class of N-alkyl-N″-cyano-N′-pyridylguanidines

Bernard Pirotte, Pascal de Tullio, Bernard Masereel, Marc Schynts, Jacques Delarge, Léon Dupont

Journal:

Helvetica Chimica Acta

Year:

1993

Language:

english

File:

PDF, 442 KB

english, 1993

19

First synthesis of 4-substituted benzenesulfonylcyanoguanidines

Bernard Masereel, Philippe Lebrun, Jean Michel Dogné, Pascal de Tullio, Bernard Pirotte, Lionel Pochet, Ousman Diouf, Jacques Delarge

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 112 KB

english, 1996

20

Synthèse, étude théorique et évaluation biologique de dérivés du 4-amino-4H-1,2,4-triazole analogues des antibiotiques β-lactamiques

B Pirotte, G Dive, J Delarge, B Masereel, L Dupont, L Thunus, M Schynts, J Coyette, JM Frère

Journal:

European Journal of Medicinal Chemistry

Year:

1992

File:

PDF, 1.39 MB

1992

21

Synthesis and pharmacology of pyrid-3-yl sulfonylureas and thioureas as astrocytic Na+ 2C1− K+ cotransporter inhibitors

B Masereel, P Renard, M Schynts, B Pirotte, P de Tullio, J Delarge

Journal:

European Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 937 KB

english, 1994

22

Synthesis and pharmacology of pyrid-3-ylsulfonylcyanoguanidines as diuretic

B Masereel, L Dupont, D Laeckmann, JF Liégeois, B Pirotte, P de Tullio, J Delarge

Journal:

European Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 685 KB

english, 1995

23

Synthesis, molecular modelling and enzymatic evaluation of (±)3,5-diphenyl-2-thioxoimidazolidin-4-ones as new potential cyclooxygenase inhibitors

Marie P. Gauthier, Catherine Michaux, Stéphanie Rolin, Caroline Vastersaegher, Xavier de Leval, Fabien Julémont, Lionel Pochet, Bernard Masereel

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 283 KB

english, 2006

24

Ligand-based and structure-based virtual screening to identify carbonic anhydrase IX inhibitors

Anne Thiry, Marie Ledecq, Alessandro Cecchi, Raphael Frederick, Jean-Michel Dogné, Caudiu T. Supuran, Johan Wouters, Bernard Masereel

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 416 KB

english, 2009

25

Design, solid-phase synthesis, and biological evaluation of novel 1,5-diarylpyrrole-3-carboxamides as carbonic anhydrase IX inhibitors

Sébastien Gluszok, Raphaël Frédérick, Catherine Foulon, Frédérique Klupsch, Claudiu T. Supuran, Daniela Vullo, Andrea Scozzafava, Jean-François Goossens, Bernard Masereel, Patrick Depreux, Laurence Go

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.69 MB

english, 2010

26

Synthesis and evaluation of β-carboline derivatives as potential monoamine oxidase inhibitors

J. Reniers, S. Robert, R. Frederick, B. Masereel, S. Vincent, J. Wouters

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.13 MB

english, 2011

27

Carbonic anhydrase inhibitors. Design of anticonvulsant sulfonamides incorporating indane moieties

Celine Chazalette, Bernard Masereel, Stéphanie Rolin, Anne Thiry, Andrea Scozzafava, Alessio Innocenti, Claudiu T. Supuran

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 283 KB

english, 2004

28

Investigation of mechanism-based thrombin inhibitors: Implications of a highly conserved water molecule for the binding of coumarins within the S pocket

Raphaël Frédérick, Caroline Charlier, Séverine Robert, Johan Wouters, Bernard Masereel, Lionel Pochet

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 286 KB

english, 2006

29

Carbonic anhydrase inhibitors. Inhibition of isoforms I, II, IV, VA, VII, IX, and XIV with sulfonamides incorporating fructopyranose–thioureido tails

Jean-Yves Winum, Anne Thiry, Khaled El Cheikh, Jean-Michel Dogné, Jean-Louis Montero, Daniela Vullo, Andrea Scozzafava, Bernard Masereel, Claudiu T. Supuran

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 321 KB

english, 2007

30

Synthesis and pharmacological evaluation of a new targeted drug carrier system: β-Cyclodextrin coupled to oxytocin

Carine Bertolla, Stéphanie Rolin, Brigitte Evrard, Lionel Pochet, Bernard Masereel

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 134 KB

english, 2008

31

NF-κB inducing kinase (NIK) inhibitors: Identification of new scaffolds using virtual screening

Jérémie Mortier, Bernard Masereel, Caroline Remouchamps, Corinne Ganeff, Jacques Piette, Raphaël frederick

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 856 KB

english, 2010

32

Indanesulfonamides as carbonic anhydrase inhibitors and anticonvulsant agents: Structure–activity relationship and pharmacological evaluation

Anne Thiry, Stéphanie Rolin, Daniela Vullo, Aurélie Frankart, Andrea Scozzafava, Jean-Michel Dogné, Johan Wouters, Claudiu T. Supuran, Bernard Masereel

Journal:

European Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 478 KB

english, 2008

33

Synthesis and biological evaluation of a new family of anti-benzylanilinosulfonamides as CA IX inhibitors

Anne Thiry, Aurélie Delayen, Laurence Goossens, Raymond Houssin, Marie Ledecq, Aurélie Frankart, Jean-Michel Dogné, Johan Wouters, Claudiu T. Supuran, Jean-Pierre Hénichart, Bernard Masereel

Journal:

European Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 486 KB

english, 2009

34

On the use of radioisotopes to study the possible synthesis by magnetron sputtering of bimetallic nanoparticles

V. Bouchat, N. Moreau, V. Valembois, K. Abbas, O. Feron, B. Gallez, U. Holzwarth, B. Masereel, C. Michiels, F. Simonelli, T. Vander Borght, S. Lucas

Journal:

Surface and Coatings Technology

Year:

2011

Language:

english

File:

PDF, 892 KB

english, 2011

35

Investigation of the inhibition mechanism of coumarins on chymotrypsin by mass spectrometry

Lionel Pochet, Marc Dieu, Raphaël Frédérick, Ann-Marie Murray, Isabelle Kempen, Bernard Pirotte, Bernard Masereel

Journal:

Year:

2003

Language:

english

File:

PDF, 226 KB

english, 2003

36

A pharmacophore model for sulphonyl-urea (-cyanoguanidine) compounds with dual action, thromboxane receptor antagonists and thromboxane synthase inhibitors

Catherine Michaux, Jean-Michel Dogné, Stéphanie Rolin, Bernard Masereel, Johan Wouters, François Durant

Journal:

European Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 640 KB

english, 2003

37

An overview of inhibitors of Na+/H+ exchanger

B. Masereel, L. Pochet, D. Laeckmann

Journal:

European Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 264 KB

english, 2003

38

Synthesis and biological evaluation of sulfonylcyanoguanidines and sulfonamidonitroethylenes as bioisosteres of hypoglycemic sulfonylureas

B Masereel, R Ouedraogo, JM Dogné, MH Antoine, P de Tullio, B Pirotte, L Pochet, J Delarge, P Lebrun

Journal:

European Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 309 KB

english, 1997

39

Synthesis, structural characterization and thromboxane A2 receptor antagonistic activity of 3-substituted 2-[(arylsulfonyl)imino]-2,3-dihydrothiazolyl derivatives

Fabrice Lacan, Martine Varache-Lembège, Joseph Vercauteren, Jean-Michel Léger, Bernard Masereel, Jean-Michel Dogné, Alain Nuhrich

Journal:

European Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 220 KB

english, 1999

40

Structure determination and comparison of BM567, a sulfonylurea, with terbogrel, two compounds with dual action, thromboxane receptor antagonism and thromboxane synthase inhibition

Catherine Michaux, Stéphanie Rolin, Jean-Michel Dogné, François Durant, Bernard Masereel, Jacques Delarge, Johan Wouters

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 260 KB

english, 2001

41

Antagonism of the TXA2 receptor by seratrodast : A structural approach

Johan Wouters, François Durant, Bernard Masereel

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 225 KB

english, 1999

42

Coumarinic derivatives as mechanism-based inhibitors of α-chymotrypsin and human leukocyte elastase

Lionel Pochet, Caroline Doucet, Georges Dive, Johan Wouters, Bernard Masereel, Michèle Reboud-Ravaux, Bernard Pirotte

Journal:

Bioorganic & Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 390 KB

english, 2000

43

PVD Synthesis and Transfer into Water-Based Solutions of Functionalized Gold Nanoparticles

Nicolas Moreau, Carine Michiels, Bernard Masereel, Olivier Feron, Bernard Gallez, Thierry Vander Borght, Stéphane Lucas

Journal:

Plasma Processes and Polymers

Year:

2009

Language:

english

File:

PDF, 376 KB

english, 2009

44

P-glycoprotein inhibition by glibenclamide and related compounds

P. E. Golstein, A. Boom, J. van Geffel, P. Jacobs, B. Masereel, R. Beauwens

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1999

Language:

english

File:

PDF, 255 KB

english, 1999

45

Surface properties and cell adhesion onto allylamine-plasma and amine-plasma coated glass coverslips

Marianne Crespin, Nicolas Moreau, Bernard Masereel, Olivier Feron, Bernard Gallez, Thierry Vander Borght, Carine Michiels, Stephane Lucas

Journal:

Journal of Materials Science: Materials in Medicine

Year:

2011

Language:

english

File:

PDF, 840 KB

english, 2011

46

Dispersion of multi-walled carbon nanotubes in biocompatible dispersants

J.-P. Piret, S. Detriche, R. Vigneron, S. Vankoningsloo, S. Rolin, J. H. Mejia Mendoza, B. Masereel, S. Lucas, J. Delhalle, F. Luizi, C. Saout, O. Toussaint

Journal:

Journal of Nanoparticle Research

Year:

2010

Language:

english

File:

PDF, 427 KB

english, 2010

47

Effects of the dispersion methods in Pluronic F108 on the size and the surface composition of MWCNTs and their implications in toxicology assessment

Jorge Mejia, Frans Tichelaar, Christelle Saout, Olivier Toussaint, Bernard Masereel, Zineb Mekhalif, Stéphane Lucas, Joseph Delhalle

Journal:

Journal of Nanoparticle Research

Year:

2011

Language:

english

File:

PDF, 809 KB

english, 2011

48

Synthesis and structural studies of a new class of heterocyclic compounds: 1,2,4-Pyridothiadiazine 1,1-dioxides, pyridyl analogues of 1,2,4-benzothiadiazine 1,1-dioxides

Pascal de Tullio, Bernard Pirotte, Léon Dupont, Bernard Masereel, Didier Laeckmann, Tchao Podona, Ousmane Diouf, Philippe Lebrun, Jacques Delarge

Journal:

Year:

1995

Language:

english

File:

PDF, 724 KB

english, 1995

49

Production and preliminary characterization of DC plasma polymerized allylamine film (PPAA) by NRA, ERD and XPS

S. Lucas, G. Genard, C. Michiels, B. Masereel, O. Feron, B. Gallez, T. Vander Borght, N. Moreau

Journal:

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

Year:

2008

Language:

english

File:

PDF, 371 KB

english, 2008

50

“Fries like” rearrangement: A novel and efficient method for the synthesis of 6-acyl-2(3H)-benzoxazolones and 6-acyl-2(3H)-benzothiazolones

Huseyin Ucar, Kim Van derpoorten, Paul Depovere, Daniel Lesieur, Majed Isa, Bernard Masereel, Jacques Delarge, Jacques H. Poupaert

Journal:

Year:

1998

Language:

english

File:

PDF, 426 KB

english, 1998

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